Sundlov JA, Garringer JA, Carney JM, Reger AS, Drake EJ, Duax WL, Gulick AM. Branchini BR, Southworth TL, Fontaine DM, Murtiashaw MH, McGurk A, Talukder MH, Qureshi R, Yetil D, Sundlov JA, Gulick AM. Gulick AM, Horswill AR, Thoden JB, Escalante-Semerena JC, Rayment I. (2002) Pentaerythritol propoxylate: a new crystallization agent and cryoprotectant induces crystal progress of 2-methylcitrate dehydratase. Gulick AM, Starai VJ, Horswill AR, Homick KM, Escalante-Semerena JC. Manoharan HT, Gallo J, Gulick AM, Fahl WE. Richard JP, Amyes TL, Malabanan MM, Zhai X, Kim KJ, Reinhardt CJ, Wierenga RK, Drake EJ, Gulick AM. Gulick AM, Hubbard BK, Gerlt JA, Rayment I. (2001) Evolution of enzymatic activities in the enolase superfamily: identification of the overall acid catalyst in the energetic site of D-glucarate dehydratase from Escherichia coli. Gulick AM, Schmidt DM, Gerlt JA, Rayment I. (2001) Evolution of enzymatic actions within the enolase superfamily: crystal constructions of the L-Ala-D/L-Glu epimerases from Escherichia coli and Bacillus subtilis. 2016) Buildings of a Nonribosomal Peptide Synthetase Module Sure to MbtH-like Proteins Assist a Extremely Dynamic Area Structure. Gulick AM, Bauer CB, Thoden JB, Rayment I. (1997) X-ray constructions of the MgADP, MgATPgammaS, and MgAMPPNP complexes of the Dictyostelium discoideum myosin motor domain. 1997) High-degree production and purification of biologically energetic proteins from bacterial and mammalian cells utilizing the tandem pGFLEX expression system.
2013) Characterization of AusA: A Dimodular Nonribosomal Peptide Synthetase Answerable for the Production of Aureusimine Pyrazinones. Gulick AM. (2017) Nonribosomal peptide synthetase biosynthetic clusters of ESKAPE pathogens. 2008) Structural characterization of a 140 degrees area movement in the two-step response catalyzed by 4-chlorobenzoate:CoA ligase. Wu R, Cao J, Lu X, Reger AS, Gulick AM, Dunaway-Mariano D. (2008) Mechanism of 4-chlorobenzoate:coenzyme a ligase catalysis. Family of native-specific monoclonal antibodies used to block catalysis. 2016) Structure-Function Studies of Hydrophobic Residues That Clamp a Basic Glutamate Side Chain throughout Catalysis by Triosephosphate Isomerase. 1992) Structural research on human glutathione S-transferase pi. 1992) Mutational substitution of residues implicated by crystal construction in binding the substrate glutathione to human glutathione S-transferase pi. 2013) Computational Screening of the Human TF-Glycome Provides a Structural Definition for the Specificity of Anti-Tumor Antibody JAA-F11. 2015) Examining Reaction Specificity in PvcB, a Source of Diversity in Isonitrile-Containing Natural Products. 2015) Experimental Support for a Single Electron-Transfer Oxidation Mechanism in Firefly Bioluminescence. Wu R, Reger AS, Lu X, Gulick AM, Dunaway-Mariano D. (2009) The mechanism of domain alternation within the acyl-adenylate forming ligase superfamily member 4-chlorobenzoate: coenzyme A ligase. Wu R, Reger AS, Cao J, Gulick AM, Dunaway-Mariano D. (2007) Rational redesign of the 4-chlorobenzoate binding site of 4-chlorobenzoate: coenzyme a ligase for expanded substrate vary.
Kholodar SA, Allen CL, Gulick AM, Murkin AS. Gulick AM, Song H, Endow SA, Rayment I. (1998) X-ray crystal structure of the yeast Kar3 motor domain complexed with Mg.ADP to 2.Three A resolution. Gulick AM, Lu X, Dunaway-Mariano D. (2004) Crystal construction of 4-chlorobenzoate:CoA ligase/synthetase in the unliganded and aryl substrate-bound states. Miller BR, Drake EJ, Shi C, Aldrich CC, Gulick AM. Sundlov JA, Shi C, Wilson DJ, Aldrich CC, Gulick AM. Manoharan TH, Gulick AM, Reinemer P, Dirr HW, Huber R, Fahl WE. Mitchell CA, Tucker AC, Escalante-Semerena JC, Gulick AM. Gulick AM, Goihl AL, Fahl WE. Shah MB, Ingram-Smith C, Cooper LL, Qu J, Meng Y, Smith KS, Gulick AM. 2018) Trapping interactions between catalytic domains and service proteins of modular biosynthetic enzymes with chemical probes. 2014) Analysis of the linker area becoming a member of the adenylation and service protein domains of the modular nonribosomal peptide synthetases. 2012) Structural and functional investigation of the intermolecular interplay between NRPS adenylation and carrier protein domains.
2016) An Open and Shut Case: The Interaction of Magnesium with MST Enzymes. 2016) 1.2 Å decision crystal structure of the periplasmic aminotransferase PvdN from Pseudomonas aeruginosa. 2006) Determination of the crystal structure of EntA, a 2,3-dihydro-2,3-dihydroxybenzoic acid dehydrogenase from Escherichia coli. 2018) Crystal Structure of the Siderophore Binding Protein BauB Bound to an Unusual 2:1 Complex Between Acinetobactin and Ferric Iron. 2009) The 2.1 A crystal structure of an acyl-CoA synthetase from Methanosarcina acetivorans reveals an alternate acyl-binding pocket for small branched acyl substrates. 2016) Structural and Functional Characterization of Aerobactin Synthetase IucA from a Hypervirulent Pathotype of Klebsiella pneumoniae. 2018) Structural and purposeful delineation of aerobactin biosynthesis in hypervirulent Klebsiella pneumoniae. 2018) Development of a High-Throughput Biochemical Assay to Screen for Inhibitors of Aerobactin Synthetase IucA. 2007) Biochemical and crystallographic analysis of substrate binding and conformational modifications in acetyl-CoA synthetase. Substitution mutations to find out amino acids crucial for binding glutathione. 1995) Mammalian glutathione S-transferase: regulation of an enzyme system to realize chemotherapeutic efficacy. 1995) Forced evolution of glutathione S-transferase to create a more efficient drug detoxication enzyme. 2013) Non-Nucleoside Inhibitors of BasE, an Adenylating Enzyme in the Siderophore Biosynthetic Pathway of the Opportunistic Pathogen Acinetobacter baumannii.
Leave a Reply